| Passing | Rushing | Receiving | Misc | Fum | Fantasy | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Player | Opp | Yds | TD | Int | Yds | TD | Yds | TD | FumTD | 2PT | Lost | Points |
Kareem Hunt RB - kc View Videos | @HOU | - | - | - | 717 | 4 | 285 | 2 | - | - | 1 | 134.20 |
| @PIT | - | - | - | 596 | 6 | 136 | 1 | - | - | - | 115.20 | |
| SEA | - | - | - | 521 | 4 | 245 | 3 | - | - | 2 | 114.60 | |
| @NYG | - | - | - | 356 | 3 | 222 | 4 | - | - | - | 99.80 | |
| JAX | - | - | - | 550 | 4 | 156 | - | - | - | - | 94.60 | |
| MIN | - | - | - | 495 | 4 | 59 | - | - | - | 1 | 77.40 | |
| @IND | - | - | - | 360 | 4 | 142 | - | - | - | - | 74.20 | |
Chris Thompson RB - was | Bye | - | - | - | 175 | 2 | 340 | 2 | - | - | 1 | 73.50 |
Devonta Freeman RB - atl View Videos | Bye | - | - | - | 353 | 5 | 81 | - | - | - | - | 73.40 |
Ezekiel Elliott RB - dal View Videos | GB | - | - | - | 393 | 2 | 134 | 1 | - | - | - | 70.70 |
Lamar Miller RB - hou | KC | - | - | - | 372 | 1 | 175 | 1 | - | - | - | 66.70 |
| NYJ | - | - | - | 117 | 2 | 269 | 1 | - | - | - | 56.60 | |
LeGarrette Blount RB - phi | ARI | - | - | - | 390 | 1 | 21 | 1 | - | 1 | - | 55.10 |
| Bye | - | - | - | 284 | 2 | 161 | - | - | - | 1 | 54.50 | |
Dalvin Cook RB - min IR | @CHI | - | - | - | 354 | 2 | 90 | - | - | - | 1 | 54.40 |
C.J. Anderson RB - den View News | Bye | - | - | - | 347 | 1 | 67 | 1 | - | - | - | 53.40 |
| @OAK | - | - | - | 281 | 1 | 114 | 1 | - | - | - | 51.50 | |
Mike Gillislee RB - ne | @TB | - | - | - | 290 | 4 | - | - | - | - | 1 | 51.00 |
Frank Gore RB - ind View News | SF | - | - | - | 288 | 2 | 100 | - | - | - | - | 50.80 |
| @MIA | - | - | - | 313 | 2 | 86 | - | - | - | 1 | 49.90 | |
| @DET | - | - | - | 104 | - | 293 | 2 | - | - | 1 | 49.70 | |
Ty Montgomery RB - gb View News | @DAL | - | - | - | 180 | 2 | 132 | 1 | - | - | - | 49.20 |
Tevin Coleman RB - atl | Bye | - | - | - | 213 | 1 | 157 | 1 | - | - | - | 49.00 |
Ameer Abdullah RB - det | CAR | - | - | - | 342 | 1 | 68 | - | - | - | - | 47.00 |
| @CIN | - | - | - | 279 | - | 189 | - | - | - | - | 46.80 | |