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| Rank | Player | Opp | NFL Fantasy Experts |
|---|---|---|---|
| 1 | Israel Abanikanda RB - NYJ | @NE | -- |
| 2 | Ameer Abdullah RB - LV | DEN | -- |
| 3 | De'Von Achane RB - MIA | BUF | -- |
| 4 | Salvon Ahmed RB - MIA | BUF | -- |
| 5 | Cam Akers RB - LA | @SF | -- |
| 6 | Tyler Allgeier RB - ATL | @NO | -- |
| 7 | Darius Anderson RB Q | Bye | -- |
| 8 | Alex Armah RB - WAS | DAL | -- |
| 9 | Tyler Badie RB - DEN | @LV | -- |
| 10 | Saquon Barkley RB - NYG | PHI | -- |
| 11 | Nick Bawden RB - NYJ | @NE | -- |
| 12 | B.J. Baylor RB - ATL | @NO | -- |
| 13 | Greg Bell RB - DET | MIN | -- |
| 14 | Nick Bellore RB - SEA | @ARI | -- |
| 15 | Eno Benjamin RB - NO | ATL | -- |
| 16 | Tank Bigsby RB - JAX | @TEN | -- |
| 17 | Raheem Blackshear RB - CAR | TB | -- |
| 18 | Khari Blasingame RB - CHI | @GB | -- |
| 19 | Brandon Bolden RB - LV | DEN | -- |
| 20 | Mike Boone RB - HOU | @IND | -- |
| 21 | Matt Breida RB - NYG | PHI | -- |
| 22 | Gary Brightwell RB - NYG | PHI | -- |
| 23 | Kennedy Brooks RB - PHI | @NYG | -- |
| 24 | Brittain Brown RB - LV | DEN | -- |
| 25 | Chase Brown RB - CIN | CLE | -- |
| 26 | Spencer Brown RB - CAR | TB | -- |
| 27 | Michael Burton RB - DEN | @LV | -- |
| 28 | Jason Cabinda RB - DET | MIN | -- |
| 29 | Michael Carter RB - NYJ | @NE | -- |
| 30 | Ty Chandler RB - MIN | @DET | -- |
| 31 | Zach Charbonnet RB - SEA | @ARI | -- |
| 32 | Julius Chestnut RB - TEN | JAX | -- |
| 33 | Nick Chubb RB - CLE | @CIN | -- |
| 34 | Corey Clement RB - ARI | SEA | -- |
| 35 | James Conner RB - ARI | SEA | -- |
| 36 | Snoop Conner RB - JAX | @TEN | -- |
| 37 | Dalvin Cook RB - MIN Q | @DET | -- |
| 38 | James Cook RB - BUF | @MIA | -- |
| 39 | Jashaun Corbin RB - NYG | PHI | -- |
| 40 | Damarea Crockett RB - DEN Q | @LV | -- |
| 41 | DeeJay Dallas RB - SEA | @ARI | -- |
| 42 | Malik Davis RB - DAL | @WAS | -- |
| 43 | Tyrion Davis-Price RB - SF | LA | -- |
| 44 | AJ Dillon RB - GB | CHI | -- |
| 45 | Gerrid Doaks RB - HOU | @IND | -- |
| 46 | J.K. Dobbins RB - BAL | PIT | -- |
| 47 | Rico Dowdle RB - DAL | @WAS | -- |
| 48 | Jerrion Ealy RB - KC | @LAC | -- |
| 49 | Trestan Ebner RB - CHI | @GB | -- |
| 50 | Chase Edmonds RB - TB | @CAR | -- |
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