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| Rank | Player | Opp | NFL Fantasy Experts |
|---|---|---|---|
| 1 | Israel Abanikanda RB - NYJ | @NE | -- |
| 2 | Ameer Abdullah RB - LV | KC | -- |
| 3 | De'Von Achane RB - MIA | ARI | -- |
| 4 | Salvon Ahmed RB - IND | @HOU | -- |
| 5 | Cam Akers RB - MIN | @LAR | -- |
| 6 | Rasheen Ali RB - BAL Q | @CLE | -- |
| 7 | Braelon Allen RB - NYJ | @NE | -- |
| 8 | Tyler Allgeier RB - ATL | @TB | -- |
| 9 | Tyler Badie RB - DEN IR | CAR | -- |
| 10 | Emani Bailey RB - KC | @LV | -- |
| 11 | Saquon Barkley RB - PHI | @CIN | -- |
| 12 | Nick Bawden RB | Bye | -- |
| 13 | Andrew Beck RB - GB | @JAX | -- |
| 14 | Trey Benson RB - ARI View News | @MIA | -- |
| 15 | Tank Bigsby RB - JAX | GB | -- |
| 16 | Raheem Blackshear RB - CAR Q View News | @DEN | -- |
| 17 | Khari Blasingame RB - CHI | @WAS | -- |
| 18 | Bye | -- | |
| 19 | Mike Boone RB - CAR | @DEN | -- |
| 20 | Matt Breida RB | Bye | -- |
| 21 | Bye | -- | |
| 22 | British Brooks RB - HOU IR | IND | -- |
| 23 | Chris Brooks RB - GB | @JAX | -- |
| 24 | Jonathon Brooks RB - CAR NFI-R | @DEN | -- |
| 25 | Brittain Brown RB - SEA | BUF | -- |
| 26 | Chase Brown RB - CIN | PHI | -- |
| 27 | Bye | -- | |
| 28 | Robert Burns RB - ATL PUP | @TB | -- |
| 29 | Michael Burton RB - DEN | CAR | -- |
| 30 | Noah Cain RB | Bye | -- |
| 31 | Michael Carter RB - ARI | @MIA | -- |
| 32 | Ty Chandler RB - MIN View News | @LAR | -- |
| 33 | Zach Charbonnet RB - SEA View News | BUF | -- |
| 34 | Julius Chestnut RB - TEN View News | @DET | -- |
| 35 | Nick Chubb RB - CLE | BAL | -- |
| 36 | Tarik Cohen RB | Bye | -- |
| 37 | Bye | -- | |
| 38 | Chris Collier RB - BAL View News | @CLE | -- |
| 39 | Bye | -- | |
| 40 | James Conner RB - ARI View News | @MIA | -- |
| 41 | Snoop Conner RB | Bye | -- |
| 42 | Dalvin Cook RB - DAL | @SF | -- |
| 43 | James Cook RB - BUF | @SEA | -- |
| 44 | Jashaun Corbin RB Q | Bye | -- |
| 45 | Blake Corum RB - LAR View News | MIN | -- |
| 46 | DeeJay Dallas RB - ARI | @MIA | -- |
| 47 | Isaiah Davis RB - NYJ | @NE | -- |
| 48 | Malik Davis RB - DAL | @SF | -- |
| 49 | Ray Davis RB - BUF | @SEA | -- |
| 50 | Tyrion Davis-Price RB - PHI | @CIN | -- |
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