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| Rank | Player | Opp | NFL Fantasy Experts |
|---|---|---|---|
| 1 | Israel Abanikanda RB - SF | CHI | -- |
| 2 | De'Von Achane RB - MIA | TB | -- |
| 3 | Salvon Ahmed RB - IND | JAX | -- |
| 4 | Rasheen Ali RB - BAL | @GB | -- |
| 5 | Braelon Allen RB - NYJ | NE | -- |
| 6 | LeQuint Allen RB - JAX | @IND | -- |
| 7 | Tyler Allgeier RB - ATL | LAR | -- |
| 8 | Tyler Badie RB - DEN | @KC | -- |
| 9 | Emani Bailey RB - CAR | SEA | -- |
| 10 | Rushawn Baker RB - NYG | @LV | -- |
| 11 | Saquon Barkley RB - PHI | @BUF | -- |
| 12 | Andrew Beck RB - NYJ | NE | -- |
| 13 | Trey Benson RB - ARI | @CIN | -- |
| 14 | Ulysses Bentley IV RB - IND | JAX | -- |
| 15 | Bye | -- | |
| 16 | Tank Bigsby RB - JAX | @IND | -- |
| 17 | Raheem Blackshear RB - CAR | SEA | -- |
| 18 | Jaydon Blue RB - DAL | @WAS | -- |
| 19 | Gary Brightwell RB - CIN | ARI | -- |
| 20 | British Brooks RB - HOU Q | @LAC | -- |
| 21 | Chris Brooks RB - GB | BAL | -- |
| 22 | Tahj Brooks RB - CIN | ARI | -- |
| 23 | Chase Brown RB - CIN | ARI | -- |
| 24 | Michael Burton RB - DEN | @KC | -- |
| 25 | Michael Carter RB - ARI | @CIN | -- |
| 26 | Nate Carter RB - ATL | LAR | -- |
| 27 | Ty Chandler RB - MIN | DET | -- |
| 28 | Zach Charbonnet RB - SEA | @CAR | -- |
| 29 | Julius Chestnut RB - TEN | NO | -- |
| 30 | Nick Chubb RB - HOU | @LAC | -- |
| 31 | Chris Collier RB - LV | NYG | -- |
| 32 | Quali Conley RB - CIN | ARI | -- |
| 33 | James Conner RB - ARI | @CIN | -- |
| 34 | James Cook RB - BUF | PHI | -- |
| 35 | Blake Corum RB - LAR | @ATL | -- |
| 36 | Jacory Croskey-Merritt RB - WAS | DAL | -- |
| 37 | DeeJay Dallas RB - ARI | @CIN | -- |
| 38 | Isaiah Davis RB - NYJ | NE | -- |
| 39 | Ray Davis RB - BUF | PHI | -- |
| 40 | Tyrion Davis-Price RB - TEN | NO | -- |
| 41 | Emari Demercado RB - ARI | @CIN | -- |
| 42 | AJ Dillon RB - PHI | @BUF | -- |
| 43 | J.K. Dobbins RB - DEN | @KC | -- |
| 44 | Elijah Dotson RB - ATL | LAR | -- |
| 45 | Rico Dowdle RB - CAR | SEA | -- |
| 46 | Donovan Edwards RB - NYJ | NE | -- |
| 47 | Clyde Edwards-Helaire RB - NO | @TEN | -- |
| 48 | Austin Ekeler RB - WAS | DAL | -- |
| 49 | Audric Estimé RB - DEN | @KC | -- |
| 50 | Travis Etienne RB - JAX | @IND | -- |
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